Bacteria to Blame in Asthma Attacks in Children, Research Suggests

ScienceDaily (Oct. 7, 2010) — Doctors have long known that viral infections can bring about asthma attacks and the shortness of breath, coughing, and wheezing associated with them. But while viral infections cannot be treated, scientists at the Danish Paediatric Asthma Centre (DPAC) at the University of Copenhagen and Gentofte Hospital have discovered that treatable bacterial infections can also cause asthma attacks. The discovery could revolutionize treatment.

"We found a significant relationship between bacterial infections and acute asthma attacks -- above and beyond the expected relationship between viral infections and attacks," says Hans Bisgaard, a professor of pediatrics at the DPAC.
The study examined 361 children between the ages of four weeks and three years to determine the presence of viral and bacterial infections during severe asthma attacks. The results conclude that the number of attacks was just as high in children with bacterial respiratory infections as in those with viral infections.
Using antibiotics to treat asthma attacks?
"This indicates that bacteria can exacerbate asthma symptoms even if they aren't infected with a virus," Professor Bisgaard says. "The findings open up an entirely new method for treating severe asthma attacks. We can't treat viral infections, but scientists will now look into whether treatment with antibiotics can help children when they have an asthma attack if they are also suffering from a bacterial infection."
"Being able to use antibiotics to treat asthma attacks in children would be revolutionary," Professor Bisgaard says.
The effects of antibiotics in treating asthma attacks will now be examined in large-scale, clinical study by the DPAC.
The research has been published in British Medical Journal on 4 October 2010.

Web address:      Link

Breastfeeding may prevent asthma

Breastfeeding may prevent asthma 

July 22nd, 2011 in Health 

Feeding a baby on only breast milk and for up to 6 months after birth can reduce their risk of developing asthma-related symptoms in early childhood, according to new research.

The study, which is published online today (21 July 2011) in the European Respiratory Journal, looked at the impact of the duration of breastfeeding and the introduction of alternative liquids or solids in addition to breast milk.

The researchers, from the Generation R Study, Erasmus Medical Center in The Netherlands, used questionnaires to gather data from over 5,000 children. They ascertained in the first 12 months after birth whether the children had ever been breastfed, when breastfeeding was stopped, and whether any other milk or solids were introduced.

Further questionnaires were completed when the children were aged 1, 2, 3 and 4 years to check whether they had any asthma-related symptoms.

The results showed that children who had never been breastfed had an increased risk of wheezing, shortness of breath, dry cough and persistent phlegm during their first 4 years, compared to children who were breastfed for more than 6 months.

The strongest links were seen with wheezing and persistent phlegm, as children were 1.4 and 1.5 times more likely to develop these symptoms if they had never been breastfed.

Children who were fed other milk or solids during their first 4 months in addition to breast milk had an increased risk of wheezing, shortness of breath, dry cough and persistent phlegm during the first 4 years, compared to children who were exclusively breastfed for their first 4 months.

While previous studies have shown a similar effect between breastfeeding and asthma risk, this research is the first that showed a link between the length of breastfeeding and the number of wheezing episodes. Also, this study found evidence that the first asthma-related symptoms occur earlier in life if children were breastfed for shorter lengths of time or not exclusively.

Dr Agnes Sonnenschein-van der Voort, researcher at Generation R and lead author from the Erasmus Medical Center in The Netherlands, said: "The link of duration and exclusiveness of breastfeeding with asthma-related symptoms during the first 4 years was independent of infectious and atopic diseases. These results support current health policy strategies that promote exclusive breastfeeding for 6 months in industrialised countries. Further studies are needed to explore the protective effect of breastfeeding on the various types of asthma in later life."

Provided by European Lung Foundation

"Breastfeeding may prevent asthma." July 22nd, 2011. http://medicalxpress.com/news/2011-07-breastfeeding-asthma.html